Ender Yıldırım

Assoc. Prof. Dr.

Address: Middle East Technical University, Mechanical Engineering Department Universiteler Mah. Dumlupinar Blv. 1, 06800, Cankaya Ankara
Telephone:
Fax:
E-mail: yender@metu.edu.tr
Nationality: Turkish

WORK EXPERIENCE

Dates (from – to)
2020 to date
Name and address of employer
METU MEMS Center, Mustafa Kemal Mah. Dumlupinar Blv. 280, 06530 Cankaya Ankara, Turkey
Type of business or sector
Research and Development
Occupation or position held
Consultant
Main activities and responsibilities
Development of biomedical micro electromechanical systems (Bio-MEMS) and microfluidic devices
Dates (from – to)
2019 to date
Name and address of employer
Middle East Technical University, Mechanical Engineering Department Universiteler Mah. Dumlupinar Blv. 1, 06800, Cankaya Ankara, Turkey
Type of business or sector
Higher Education and Research
Occupation or position held
Assoc. Prof. Dr.
Main activities and responsibilities
Lecturing; Research
Dates (from – to)
2013 to 2019
Name and address of employer
Çankaya University, Mechanical Engineering Department Eskişehir Yolu 29. Km. Yukarıyurtçu Mahallesi Mimar Sinan Caddesi No:4 06790, Etimesgut Ankara, Turkey
Type of business or sector
Higher Education and Research
Occupation or position held
Assoc. Prof. Dr.
Main activities and responsibilities
Lecturing; Research
Dates (from – to)
2012 to 2013
Name and address of employer
Leiden University, Leiden Academic Center for Drug Research, Division of Analytical Biosciences, Gorlaeus Building, Einsteinweg 55, 2333 CC, Leiden, Netherlands
Type of business or sector
Higher Education and Research
Occupation or position held
Visiting Researcher
Main activities and responsibilities
Research
Dates (from – to)
2010 to 2012
Name and address of employer
Çankaya University, Mechanical Engineering Department Eskişehir Yolu 29. Km. Yukarıyurtçu Mahallesi Mimar Sinan Caddesi No:4 06790, Etimesgut Ankara, Turkey
Type of business or sector
Higher Education and Research
Occupation or position held
Instructor
Main activities and responsibilities
Lecturing; Curriculum Development
Dates (from – to)
2008 to 2010
Name and address of employer
Çankaya University, Industrial Engineering Department Eskişehir Yolu 29. Km. Yukarıyurtçu Mahallesi Mimar Sinan Caddesi No:4 06790, Etimesgut Ankara, Turkey
Type of business or sector
Higher Education and Research
Occupation or position held
Instructor
Main activities and responsibilities
Lecturing
Dates (from – to)
2004 to 2008
Name and address of employer
Çankaya University, Industrial Engineering Department Eskişehir Yolu 29. Km. Yukarıyurtçu Mahallesi Mimar Sinan Caddesi No:4 06790, Etimesgut Ankara, Turkey
Type of business or sector
Higher Education and Research
Occupation or position held
Research Assistant
Main activities and responsibilities
Teaching Assistance
Dates (from – to)
2002 to 2004
Name and address of employer
Middle East Technical University, Mechanical Engineering Department Universiteler Mah. Dumlupinar Blv. 1, 06800, Cankaya Ankara, Turkey
Type of business or sector
Higher Education and Research
Occupation or position held
Research Assistant
Main activities and responsibilities
Teaching Assistance

EDUCATION AND TRAINING

Dates (from – to)
2005-2011
Name and type of organization providing education and training
Middle East Technical University, Graduate School of Natural and Applied Sciences, Mechanical Engineering, Ankara, Turkey
Principal subjects/occupational
Micro Electromechanical Systems (MEMS) fabrication techniques, Electrostatic Actuation Principles, Biomedical MEMS, Microfluidics, Microvalves
Title of qualification awarded
Ph.D.
Dates (from – to)
2002-2005
Name and type of organization providing education and training
Middle East Technical University, Graduate School of Natural and Applied Sciences, Mechanical Engineering, Ankara, Turkey
Principal subjects/occupational
Micro Electromechanical Systems (MEMS) fabrication techniques, Electrostatic Actuation Principles, Materials Characterization and Testing
Title of qualification awarded
M.Sc.
Dates (from – to)
1997-2002
Name and type of organization providing education and training
Middle East Technical University, Mechanical Engineering Department, Ankara, Turkey
Principal subjects/occupational
Bachelor Study at Mechanical Engineering Department
Title of qualification awarded
Mechanical Engineer

PERSONAL SKILLS AND COMPETENCES

MOTHER TONGUE
Turkish
OTHER LANGUAGES
English
Reading skills
Excellent
Writing skills
Excellent
Verbal skills
Excellent
SOCIAL SKILLS AND COMPETENCES
Living and working with other people, in multicultural environments, in positions where communication is important and situations where teamwork is essential (for example culture and sports), etc.
Dr. Yıldırım is experienced in working in multinational research groups (research groups at Leiden University Academic Center for Drug Research, Netherlands and Warwick University, Warwick Manufacturing Group, UK). Dr. Yıldırım also has experience in setting up new laboratories (Microfluidic Design and Characterization Lab. and Undergraduate Design Lab. at Cankaya University, Mechanical Engineering Department,Turkey). He is currently the co-PI of Micromanufacturing Lab. at Middle East Technical University Mechanical Engineering Department, Turkey.
ORGANIZATIONAL SKILLS AND COMPETENCES
Coordination and administration of people, projects and budgets; at work, in voluntary work (for example culture and sports) and at home, etc.
Dr. Yıldırım have led and completed one national funded research project. He is currently leading 2 national funded projects. Dr. Yıldırım also took part in 1 international and 2 national funded research projects.
TECHNICAL SKILLS AND COMPETENCES
With computers, specific kinds of equipment, machinery, etc.
Dr. Yıldırım has hands-on clean-room experience exceeding 3 years on MEMS fabrication methods (particularly photolithography, physical and chemical vapor deposition techniques, wet and dry etching techniques). He is also experienced in micromanufacuring techniques (particularly hot embossing, ultrasonic embossing, and micromilling) for fabricating plastic miniature devices (e.g. lab-on-a-chip devices). Dr. Yıldırım is experienced in design of microfluidic devices and components (e.g. droplet based microfluidic systems for single-cell analysis, capillary driven microfluidic systems for analytical purposes, inertial microfluidic systems for rare cell detection, organ-on-a-chip systems, electrostatic and electromagnetic microvalves and micropumps ).
OTHER SKILLS AND COMPETENCES
Competences not mentioned above.
DRIVING LICENSE(S)

AUTHORED OR CO-AUTHORED ARTICLES

ARTICLES IN BOOK CHAPTERS 1. Eryılmaz, M., Yıldırım, E. and Tamer, U., Lab on a chip: A versatile integration with spectroscopic techniques. In Handbook on Miniaturization in Analytical Chemistry, Elsevier, 139-152, 2020.
ARTICLES IN PEER REVIEWED JOURNALS 1. Yalçın, Y. D., Töral, T. B., Sukas, S., Yıldırım, E., Zorlu, Ö., Gündüz, U., and Külah, H. (2021). “A microfluidic device enabling drug resistance analysis of leukemia cells via coupled dielectrophoretic detection and impedimetric counting” Scientific Reports, vol. 11, 13193, 2021.

2. Atay, A., Topuz, A., Sarıarslan, B., Yıldırım, E., Charmet, J., Couling, K., and Çetin, B. (2021). “Flow rate-controlled pipetting for microfluidics: second-generation flexible hydraulic reservoir (FHRv2)”, Microfluidics and Nanofluidics, vol. 25, 3, 2021.

3. Özkayar, G., Mutlu, E., Şahin, Ş., Demircan Yalçın, Y., Töral, T, Külah, H, Yıldırım, E., Zorlu, Ö, and Özgür. E., "A Novel Microfluidic Method Utilizing a Hydrofoil Structure to Improve Circulating Tumor Cell Enrichment: Design and Analytical Validation" Micromachines, no. 11, 981, 2020.

4. Atik, A.C., Özkan, M.D., Özgür, E., Külah, H. and Yıldırım, E., “Modeling and fabrication of electrostatically actuated diaphragms for on-chip valving of MEMS-compatible microfluidic systems”, Journal of Micromechanics and Microengineering, vol. 30, no. 11, 115001, 2020.

5. Dogan, Ü., Kasap, E.N., Sucularlı, F., Yildirim, E., Tamer, U., Cetin, D., Suludere, Z., Boyaci, I.H. and Ertas, N., “Multiplex enumeration of Escherichia coli and Salmonella enteritidis in a passive capillary microfluidic chip”, Analytical Methods, vol. 12, no. 30, 3788-3796, 2020.

6. J. Charmet, R. Rodrigues, E. Yildirim, P. K. Challa, B. Roberts, R. Dallmann, Y. Whulanza, “Low Cost Microfabrication Tool Box”, Micromachines, vol. 11, no. 2, 135, 2020.

7. F. Çoğun, M.A.S. Arıkan, E. Yildirim, “Investigation of process-affected zone in ultrasonic embossing of microchannels on thermoplastic substrates”, Journal of Manufacturing Processes, vol. 50, 394-402, 2020.

8. E.N. Kasap, Ü. Doğan, F. Çoğun, E. Yildirim, İ.H. Boyacı, D. Çetin, Z. Suludere, U. Tamer, N. Ertaş, “Fast fluorometric enumeration of E. coli using passive chip”, Journal of Microbiological Methods, vol. 164, 105680, 2019.

9. S. Mergen, E. Yıldırım, H. Türkoğlu, “Numerical study on effects of computational domain length on flow field in standing wave thermoacoustic couple”, Cryogenics, vol. 98, pp. 139-147, 2019.

10. U. Hatipoğlu, B. Çetin, E. Yildirim, “A novel zero-dead-volume sample loading interface for microfluidic devices: Flexible Hydraulic Reservoir (FHR)”, Journal of Micromechanics and Microengineering, vol. 28, no. 9, pp. 097001, 2018.

11. B. Gjergjizi, F. Çoğun, E. Yildirim, M. Eryılmaz, Y. Selbes, N. Sağlam, U. Tamer, “SERS Based Ultrafast and Sensitive Detection of Luteinizing Hormone in Human Serum Using a Microchip”, Sensors and Actuators B, vol. 269, pp. 314-321, 2018.

12. F. Çoğun, E. Yildirim, M.A. S. Arıkan, “An Investigation on Effects of Hot Embossing Parameters on Replication of a Microfluidic Mold”, Materials and Manufacturing Processes, vol. 32, no. 16, pp. 1838-1844, 2017.

13. E. Yildirim, “Analysis and Testing of a Contraction-and-Expansion Micromixer for Micromilled Microfluidics”, Microsystem Technologies, vol. 23, no. 10, pp. 4797–4804, 2017.

14. E. Yildirim, Ç. Arpali, S. A. Arpali, “Implementation and Characterization of an Absorption Filter for On-Chip Fluorescent Imaging”, Sensors and Actuators B: Chemical, vol. 242, pp. 318-323, 2017.

15. E. Yildirim, S.J. Trietsch, J. Joore, A. van den Berg, T. Hankemeier, P. Vulto, “Phaseguides as tunable passive microvalves for liquid routing in complex microfluidic networks”, Lab on a Chip, vol. 14, no. 17, pp. 3334-3340, 2014.

16. C. Phurimsak, E. Yildirim, M.D. Tarn, S.J. Trietsch, T. Hankemeier, N. Pamme, P. Vulto, “Phaseguide assisted liquid lamination for magnetic particle-based assays”, Lab on a Chip, vol. 14, no. 13, pp. 2334-2343, 2014.

17. E. Yildirim, M.A. Sahir Arıkan, H. Külah, “A normally closed electrostatic parylene microvalve for micro total analysis systems”, Sensors and Actuators A: Physical, vol. 181, pp. 81-86, 2012.

18. E. Yildirim, H. Külah, “Electrostatic energy harvesting by droplet based multi-phase microfluidics”, Microfluidics and Nanofluidics, vol. 13, no. 1, pp. 107-111, 2012.

19. E. Yıldırım, H. Külah, “Analysis and characterization of an electrostatically actuated in-plane parylene microvalve”, Journal of Micromechanics and Microengineering, vol. 21, p. 105009, 2011.

20. E. Yildirim, “Modeling and Analysis of a Microfluidic Capillary Valve”, Journal of Polytechnic, vol. 20, no. 2, pp. 487-494, 2017.
ARTICLES IN PEER REVIEWED CONFERENCES AND SYMPOSIUMS (INTERNATIONAL CONFERENCES ONLY) 1. Y. Demircan Yalcin, T. B. Toral, S. Sukas, E.Yildirim, O. Zorlu, U. Gunduz, H. Kulah, “Dielectrophoretic detection of imatinib resistance in K562 cells using a lab-on-a-chip system”, 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, pp. 13568-1359, Basel, Switzerland, 2019.

2. C. Arpali, E. Yildirim, S. A. Arpali, “Fluorescent on-chip imager by using a tunable absorption filter”, The European Conference on Lasers and Electro-Optics, pp. CL_2_3, Munich, Germany, 2017.

3. M.D. Ozkan, M.K. Aslan, A.C. Atik, E. Ozgur, E. Yildirim, H. Kulah “Droplet Based Cell Screening System Integrated with CMOS Image Sensor and Android-Based Application”, 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, pp. 681–682. Savannah, Georgia, USA, 2017.

4. E.E. Ahi, A. Gumustas, H. Ciftci, M.G. Caglayan, Y.S. Selbes, F. Cogun, E. Yildirim, U. Tamer, “Chip-Based Immunomagnetic Separation of Human Chorionic Gonadotropin”, International Conference: 10th Aegean Analytical Chemistry Days, Canakkale, Turkey, 2016.

5. U. Dogan, E. Kasap, F. Cogun, E. Yildirim, D. Cetin, Z. Suludere, I.H. Boyaci, N. Ertas, U. Tamer, “Simultaneous Detection of Two Different Bacteria Using QDs and MNPs”, International Conference: 10th Aegean Analytical Chemistry Days, Canakkale, Turkey, 2016.

6. F. Cogun, E. Yildirim, “Effect of Preheating on Channel Geometry and Surface Texture in Fabrication of Plastic Microfluidic Chips by Ultrasonic Hot Embossing”, EMBL Conference: Microfluidics 2016, Heidelberg, Germany, 2016.

7. A.C. Atik, M.D. Ozkan, H. Kulah, E. Ozgur, E. Yildirim, “A Novel Cell Sorting Structure to Improve Droplet Based Single Cell Encapsulation”, EMBL Conference: Microfluidics 2016, Heidelberg, Germany, 2016.

8. M. Parsian, A.C. Atik, M.D. Ozkan, U. Gunduz, H. Kulah, E. Ozgur, E. Yildirim, “On-Chip Insulated Micro Well Array for Cell Viability Assays”, EMBL Conference: Microfluidics 2016, Heidelberg, Germany, 2016.

9. E.N. Kasap, F. Cogun, E. Yildirim, I.H. Boyaci, D. Cetin, Z. Suludere, U. Tamer, N. Ertas, “Microchip Based Determination of Bacteria by In-chip Sandwich Immunoassay”, International Multidisciplinary Symposium on Drug Research and Development, Eskisehir, Turkey, 2015.

10. E. Yildirim, S.J. Trietsch, J. Joore, T. Hankemeier, P. Vulto, “Phaseguides: A Toolbox for Passive Microfluidics”, EMBL Conference: Microfluidics 2014, Heidelberg, Germany, 2014.

11. E. Yildirim, “Analysis and Testing of a Micromixer for Precision Milled Microchannel Networks”, EMBL Conference: Microfluidics 2012, Heidelberg, Germany, 2012.

12. E. Yildirim, S.J. Trietsch, J. Joore, A. van den Berg, T. Hankemeier, P. Vulto, “Phaseguides: Tunable Passive Microvalves for Liquid Routing in Complex Microfluidic Networks”, Flow 14, Enschede, Netherlands, 2014.

13. C. Phurimsak, E. Yildirim, S.J. Trietsch, T. Hankemeier, M.D. Tarn, N. Pamme, P. Vulto, “Phaseguide Assisted Liquid Lamination for Magnetic Bead Based Assays”, 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2013), Freiburg, Germany, 2013.

14. E. Erdil, K. Topalli, O. Zorlu, T. Toral, E. Yildirim, H. Kulah, O. Aydın Civi, “A Reconfigurable Microfluidic Transmitarray Unit Cell”, 7th European Conference on Antennas and Propagation, Gothenburg, Sweden, 2013.

15. E. Yildirim, E. Ozgur, H. Kulah, “A Droplet based Multi-Drug Screening System Controlled with Electrostatic Microvalves”, 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2012), Okinawa, Japan, 2012.

16. E. Yildirim, M.A.S. Arikan, H. Kulah, “An Electrostatically Actuated Parylene Microvalve for Lab-on-a-Chip Applications”, 16th International Conference on Solid State Sensors, Actuators and Micro Systems (Transducers 2011), Beijing, China, 2011.

17. E. Yildirim, A. Koyuncuoglu, H. Kulah, “An Electrostatic Parylene Microvalve for Controlling In-Plane Flow”, 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2009), Jeju, Korea, 2009.
PROJECTS DIRECTED 1. Development and Application of an Ultrasonic-based Method for Fabrication of Metal Layers with Controlled Surface Quality for Thermoplastic Lab-on-a-chip Systems, PI, Scientific and Technological Research Council of Turkey, Grant # 121M427, ongoing.

2. Numerical and Experimental Investigation of the Effect of the Corner Angle of the Phaseguides on Capillary Pressure in Micromilled Thermoplastic Microfluidic Systems, PI, Middle East Technical University Scientific Research Projects Coordination Unit, GAP-302-2021-10574, ongoing

3. Development, implementation, and testing of droplet based, integrated, high-throughput, on-chip, multi-drug screening systems, PI, Scientific and Technological Research Council of Turkey, Grant # 114E098, Oct. 2014 – Oct. 2017.
REGISTERED PATENTS 1. Micropump for Microfluidic Systems and Operation Method Thereof, TR 2019/19668
2. Phase Shifting Method for Reconfigurable Transmitarrays and Reflectarrays and a Unit Element Thereof, TR 2015/11895